Avoiding harm…
Are any adverse effects likely on subjects, researchers, institutions or communities from the carrying out of the research and its consequences, including the publication of findings?

Have all reasonable steps been taken to eliminate the risk of harm? If the objectives cannot be achieved without risk of harm, should the project be abandoned? Is there any justification for continuing with it?

Treating fairly…
Do researchers and subjects get the resources and support they need to carry out the research and to cope with its impact, not merely during its execution but also after its completion?
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