Kidney disorders. The main reason for high creatinine levels is a malfunctioning kidney. Many conditions, such as acute kidney injury and chronic kidney disease, kidney infections or obstructions in the urinary tract, can cause high creatinine levels.

Dehydration: Insufficient intake of fluids or excessive loss of fluid due to vomiting, sweating or diarrhoea can result in increased urine output and, in the short term, increased levels of creatinine.

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