Before we discuss the early signs and symptoms, let us understand the Vitiligo symptoms causes first. In hindsight, we know that permanent damage to the melanin-producing cells leads to the onset of vitiligo.

But is that all? Surprisingly no. Multiple factors actively contribute to the onset and progress of the disease.

Autoimmune disorder – This happens when the body’s immune system mistakes the healthy melanin-producing cells (melanocytes) as foreign bodies, attacking and damaging them in the process. In the long run, the immune system produces antibodies against these melanocytes, killing them in the process and forming white or light-colored patches on the body.
Genetic issues – Studies indicate that our bodies have 30+ genes, which increase our risk of vitiligo. So, any kind of prevalent genetic mutation in one of these 30 genes can result in vitiligo in the patient.
Stress – Stress that is induced after a severe injury is another potential factor that enhances the risks of vitiligo in patients.
External triggers – Chronic exposure to ultraviolet radiation from the sunlight or toxic chemicals leads to enhanced risks of melanocyte depletion and damage in the body.
Existing autoimmune disorder – If you are already diagnosed with an autoimmune disorder, that further enhances the risks of you developing vitiligo.
In hindsight, many patients coming for a consultation at Kayakalp Global often have this misconception that 100% of vitiligo cases are due to genetic predisposition, which isn’t the case. Instead, roughly 30% of vitiligo cases are genetic.
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