Biology

• Haptens are non-immunogenic small molecules and usually need conjugating to carrier proteins, such as BSA (bovine serum albumin) and KLH (keyhole limpet hemocyanin) in order to expose the small molecule epitope in some ways. Besides, haptens are administered with adjuvants to ensure a high-quality immune response further. https://small-molecule-antibody.creative-biolabs.com/custom-services-for-anti-hapten-antibody.htm. [more]

  by cailynnjohnson, Biology,

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• The critical step of design and modification of hapten is by considering the choice of appropriate modification sites, selection of spacer arm length, selection of linking spacer and carrier, and the coupling method. Based on the chemical criteria, theoretical studies, and molecular modeling techniques, Creative Biolabs can offer the molecular structure design of hapten. These haptens could have a certain degree of complexity or rigidity to maintain the original molecular. [more]

  by cailynnjohnson, Biology,

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• Immune checkpoints are regulators to enhance or moderate immune responses. Immune checkpoint mechanisms are often activated to suppress the nascent anti-tumor immune response, which leads to the development of several immune checkpoint inhibitors, such as antibodies, peptides, and small molecular drugs for cancer therapy. Learn more about ICI research: https://immune-checkpoint.creative-biolabs.com/services.htm. [more]

  by cataliesw, Biology,

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• High-throughput sequencing by whole genome or transcriptome amplification at single-cell level reveals the genetic structure and gene expression status of individual cells, reflecting intercellular heterogeneity. Single cell immune profiling is more suitable for solving a small number of special sample studies, heterogeneous population analysis, and the search for simultaneous or mutually exclusive genomic changes, which is limited by bulk analysis. Learn more about scTCR. [more]

  by cataliesw, Biology,

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• The outbreak of a new coronavirus (SARS-CoV-2) is driving China’s urgent public health actions, as well as an international concern. Infection prevention and control through diagnostic testing and quarantine has become critical. Creative Biolabs offers an in vitro diagnostic (IVD) reagent development platform for improved detection and control of SARS-CoV-2. Learn more about IVD reagents SARS-CoV-2:. [more]

  by cataliesw, Biology,

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• Aided by our first-class platform and scientific team, Creative Biolabs provides a collection of AAV services, including but not limited to: vector design, purification, titration, toxicity and safety determination. These all-around services can meet customers' demands in basic research and preclinical applications. https://www.creative-biolabs.com/gene-therapy/adeno-associated-virus-vector.htm. [more]

  by cailynnjohnson, Biology,

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• AAV has low toxicity, apparent lack of pathogenicity and provides long-term transgene expression through chromosomal integration. Using the basic principles of molecular biology and laboratory techniques, Creative Biolabs provides a wide variety of AAV vectors for both basic research and clinical applications. https://www.creative-biolabs.com/gene-therapy/adeno-associated-virus-vector.htm. [more]

  by cailynnjohnson, Biology,

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• Compared with other gene delivery vectors, recent advancements in various adeno-associated virus (AAV) engineering have greatly expanded their applications for gene therapy as an ideal gene vehicle. Creative Biolabs has successfully established a state-of-art gene-therapy platform to offer diverse services form vector design to efficacy testing, to satisfy multiple research and clinical application demands of worldwide clients.. [more]

  by cailynnjohnson, Biology,

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• RNA interference (RNAi) has become another important tool in human gene therapy, enabling scientists to move on from classical gene transfer to gene silencing methods or combinations. At Creative Biolabs, we are currently able to provide AAV vector design and construction services for the delivery of RNAi. https://www.creative-biolabs.com/gene-therapy/aav-vectors-for-delivery-of-rnai.htm. [more]

  by cailynnjohnson, Biology,

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• To overcome these limitations of therapeutic antibodies for immune checkpoints, Creative Biolabs offers immune checkpoint targeted small molecule drug development services to assist our customers with immune checkpoint research and drug development goals. https://immune-checkpoint.creative-biolabs.com/immune-checkpoint-targeted-small-molecule-drug-development.htm. [more]

  by cailynnjohnson, Biology,

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• Immune checkpoints refer to a series of molecules expressed on immune cells, regulating the degree of immune activation. They play an essential role in preventing the occurrence of autoimmunity. At Creative Biolabs, we are proud of offering immune checkpoint targeted peptide selection services to accelerate your immune checkpoint drug development projects.https://immune-checkpoint.creative-biolabs.com/immune-checkpoint-targeted-peptide-selection.htm. [more]

  by cailynnjohnson, Biology,

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• Based on the common checkpoint proteins, Creative Biolabs has developed high-quality stable cell lines expressing immune checkpoints to accelerate your immunotherapy discovery projects. Our stable cell lines are suited for manufacturing checkpoint antibodies, drug screening, and pharmacological and toxicological studies. https://immune-checkpoint.creative-biolabs.com/immune-checkpoint-stable-cell-line-development.htm. [more]

  by cailynnjohnson, Biology,

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• Our comprehensive service portfolio includes polyclonal antibody discovery and development, monoclonal antibody (mAb) discovery and development, antibody fragment discovery and development, antibody characterization, antibody engineering and optimization, antibody production, and manufacture. https://immune-checkpoint.creative-biolabs.com/immune-checkpoint-antibody-development.htm. [more]

  by cailynnjohnson, Biology,

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• Various Inlet Reservoir Options for Genizer High-Pressure Homogenizer Genizer offers a range of inlet reservoirs from precise syringes, hoses, to cylinders for your diverse sampling needs with Genizer high-pressure homogenizer.. [more]

  by JenniferGenizer, Biology,

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• https://www.youtube.com/watch?v=w1q9xrGMvPU&t=1s Genizer High-Pressure Homogenizer Inlet Reservoir Options Genizer offers a range of inlet reservoirs from precise syringes, hoses, to cylinders for your diverse sampling needs with Genizer high-pressure homogenizer. . [more]

  by JenniferGenizer, Biology,

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