Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), also known as CD152, ALPS5, CELIAC3, GRD4, GSE, or IDDM12, is a type of CD28 homolog molecule that plays an important role in regulating T cell activation. CTLA-4 is normally present in the vesicles of cells and is then transported to the immune synapse formed between T cells and antigen-presentation cells (APCs) and inhibits further activation of T cells by blocking T cell receptors and their signaling pathways. Learn more: https://immune-checkpoint.creative-biolabs.com/ctla-4-immune-checkpoint-molecule-for-drug-development.htm
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