
kosheekaa's Updates (44)
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Stem Cells For Aging A major cause of the condition is attributed to chronic inflammation. The term “Inflammaging” has been introduced to describe the inflammation leading to aging. Read More:- https://kosheeka.com/stem-cells-for-aging/
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Stem Cells for MS According to a population-based estimate (2019), 300,000 to 400,000 individuals are affected by multiple sclerosis (MS): the most common progressive neurologic disease in the United States. The disease is considered a chronic inflammatory disease of the central nervous system (CNS) that leads to demyelination and axonal loss. Read More:- https://kosheeka.com/mscs-for-multiple-sclerosis/
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Application Of Biomarkers In Clinical Drug Research Drug discovery and development extensively drives biomedical research and primary cell culture has been a very important turning point for the drug development domain. Along with primary cell culture, a critical factor in drug discovery is the study of biomarkers. Read More:-Benefits of Tissue Culture in Cancer Research and Treatment Primary cells culture refer to the removal of tissue from an organism and maintaining them in an appropriate medium to allow their division. One approach involves placing a piece of tissue in a glass or plastic vessel followed by bathing it in a medium. Division and growth of primary cell occur when cells separate from the tissue piece. In another approach, the tissue is treated with enzymes to digest the attaching materials of...Cell Culture Tips Read More:- https://kosheeka.com/simple-lab-tips-for-primary-cell-culture/ #cellculturehood #tissueculturehood #cellculturehoodpriceCell Culture Hood Primary cell culture is an expanding technology for several biomedical applications like tissue culture, 3D Cell Culture, bioscaffolds, 3D bioprinting, organoid culture etc. Researchers have been utilizing this technology as an efficient ethical alternative to animal experiments and as a physiologically in vivo-mimicking alternative to culturing continuous cell lines.How To Overcome The Challenges In Cryopreservation? Cryopreservation has become one of the major steps to focus on enhancing commercial and clinical cellular experiment-based cell culture process. Non-optimized substandard protocols and reagents used in cell culture can lead to damage of cells and lower cell viability. Besides that, the lack of optimized protocols in cell culture practice might also lead to decreased cell functionality, batch variation, genetic variations, and the...Overview Of Car-T Cell Therapy CAR-T cell therapy is a type of treatment where the patient’s T cells are modified in the laboratory for attacking the cancer cells. This type of modification involves adding the gene for a special receptor that binds to a certain cancer cell protein. The special receptor is named CAR or chimeric antigen receptor. CAR-T cell therapy is primarily prevalent for treating blood cancers, with FDA approvals in B cell Acute Lymphoblastic leukemia (ALL) and...Recombinant Proteins As per the central dogma, protein production by translation is possible after RNA transcription and it all begins with DNA replication. In simpler terms, DNA sequence provides instructions for protein synthesis, and thus a gene expression results in protein expression. The recombinant DNA technology, also known as DNA cloning or gene cloning, involves the transfer of foreign DNA into an organism, leading to the amplification of the foreign DNA followed by protein...Basal Media Cell Culture The task of choosing cell culture media for use with your primary cells is surely daunting. Therefore, if you are thinking of replicating a formulation of media from any previously published report or if you are optimizing your nutrient or classical media, it is important to understand the consequences of this media choice for your primary cell culture maintenance and research. Read More:-Mammary Epithelial Cell Carcinoma Mammary carcinoma exhibit both inter-and intra-tumoral heterogeneous nature. Several study reports have indicated that human mammary epithelial cell cancers exhibit diverse phenotypes according to pathological features and therapy response. Studies have identified distinct gene profiles to classify mammary carcinoma cell lines. Read more:-Human Primary Cells Vs Immortal Cell Lines In biomedical research and development, scientists mostly use cultured cell lines as models because they offer easy, inexpensive, and stable platforms. However, cell lines fail to grasp the microenvironment physiology that occurs in vivo. Human primary cells come to the rescue in this situation! Primary cell culture portrays the complex physiological cell behavior and therefore represents the in vivo microenvironment better. Once you decide on...How Primary Cells Are Important For In Vitro ADMET? ADME is the abbreviation for Absorption, Distribution, Metabolism, and Excretion. These ADME studies are designed to investigate the metabolism and processing of a chemical compound by a living organism. When toxicology tests are a part of this process, the acronym becomes ADMET with the last T for ‘Toxicology’. Read more:-primary Cells VS Cell Lines Human primary cells do not live forever in passages and undergo senescence. With more passage numbers, primary cells also start showing morphological and functional changes. Therefore, it is always advised to use primary cells of lower passage numbers. Furthermore, primary cells also give an advantage of not using animal models, thus having an ethical upper hand. Read more:-CD 34 The treatment of several diseases has shown promise with the use of CD 34+ cells ranging from diabetes mellitus to cancer to autoimmune disorders and cardiovascular disease (CVD) (Mackie and Losordo, 2011). Thus, these cells have a wide range of applications to treat diseases and improve the quality of life. Read more:- https://kosheeka.com/magic-of-cd-34-positive-cells/