Biology

  • The information currently available and ribosome-specific targets serve as effective roadmaps for creating more potent ribosome-associated inhibitors. We at Creative Biolabs are happy to offer our global clientele thorough ribosome analysis services to expedite your research endeavors. Learn more about Ribosome Inhibition-related Targets: https://ribosome.creative-biolabs.com/ribosome-inhibition-related-targets.htm. [more]
    by cataliesw, Biology,
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  • Creative Biolabs has sufficient expertise in the development, production, and distribution of rodent disease models. Particularly, we can provide 5/6 nephrectomy model induced in both rats and mice for various investigation objectives. Learn more: https://www.creative-biolabs.com/drug-discovery/therapeutics/5-6-nephrectomy-model.htm. [more]
    by cataliesw, Biology,
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  • Exosomes are 30-150 nm tiny vesicles secreted by most cell types in vivo and in vitro. They are found in all body fluids including plasma, serum, saliva, urine, amniotic fluid, malignant ascite fluids, and cultured medium of cell cultures. Learn more: https://www.creative-biolabs.com/exosome/services.htm. [more]
    by cataliesw, Biology,
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  • In recent years, a probiotic called Lactobacillus gasseri (L. gasseri) has received extensive attention. It is believed that this kind of bacteria can help the human body by inhibiting harmful bacteria, which in turn can enhance immune function and help digestion. Learn more: https://live-biotherapeutic.creative-biolabs.com/lactobacillus-gasseri.htm. [more]
    by cataliesw, Biology,
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  • The blood-brain barrier (BBB) is unique because it has selective permeability (which also changes in some diseased conditions). The BBB is a complex system made up of a structurally distinct, continuous endothelial cell layer separating the blood from the extracellular fluid of the brain. The luminal plasma membrane of the endothelial cells is directed towards the blood, while the abluminal plasma membrane faces the brain. Learn more about in vitro bbb model:. [more]
    by cataliesw, Biology,
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  • Recent research has shown that PD-1 and PD-L1/PD-L2 pathway plays important roles in various cancers, including breast cancer, lung cancer, colorectal cancer, gastric cancer, bladder cancer, pancreatic cancer, prostate cancer, and DLBCL tumor. In this case, inhibitors targeting PD-1/PD-L1 have been reported for cancer therapy, and some of them are approved by FDA. Learn more: https://immune-checkpoint.creative-biolabs.com/pd-1-and-pd-l1-pd-l2-pathway.htm. [more]
    by cataliesw, Biology,
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  • Factors for iPSCs generation have been identified including Oct-3/4, Sox gene family, Klf family, Myc family, Nanog, and LIN28. Genes used for the induction can be effectively introduced and integrated into the genome of the somatic cells via a retroviral vector. However, retroviral delivery may increase the risk of virus-induced tumor formation. To overcome this issue, researchers have attempted to use the PiggyBac transposon system to effectively deliver the key. [more]
    by cataliesw, Biology,
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  • Creative Biolabs proudly offers clodronate liposomes. Clodronate liposomes are composed of clodronate molecules encapsulated in neutral liposomes, which are able to achieve the macrophage depletion after a single intravenous or intraperitoneal administration. Clodronate molecules encapsulated in small liposomes present superior activity, physical and chemical stability. Learn more about liposome clodronate:. [more]
    by cataliesw, Biology,
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  • Strategic Science and Technology: Microfluidic Chips Microfluidic chips have garnered significant interest from both academic and industrial sectors since their inception. The launch of the journal "Lab on a Chip" in 2001 marked a pivotal moment, quickly establishing itself as a cornerstone publication and catalyzing further global research in microfluidic chips. In 2004, Business 2.0 magazine featured chip laboratories prominently, identifying them among the. [more]
    by sherwinbrown, Biology,
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  • Deciphering the Importance of Single-Cell Sequencing The term "single cell" refers to an individual cell, isolated and examined on its own. Analysis conducted specifically on individual cells is collectively referred to as single-cell sequencing analysis, while sequencing performed on these isolated cells is termed single-cell sequencing. Sequencing multiple cells or a group of cells falls outside the realm of single-cell sequencing. For instance, common genetic. [more]
    by sherwinbrown, Biology,
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  • Bispecific Antibodies: A Rising Force in Revolutionary Cancer Treatment In the realm of cancer therapy, immunotherapy has emerged as a beacon of hope, surpassing traditional methods. Monoclonal antibodies, renowned for their precision in targeting specific molecules, have played a crucial role in cancer treatment. However, their effectiveness is often limited by the complexities of tumor development when focusing on a single point. Enter bispecific antibodies (bsAbs), a. [more]
    by sherwinbrown, Biology,
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